This episode answers the question of how our bodies avoid absolute chaos when we have two X chromosomes. Featuring the story of a brilliant female scientist - Dr. Mary Lyon, the experiments that led to her breakthrough discovery, and how it is helping patients today. Cat-lovers, never fear, the magic and mystery of calico cats is also covered!
Sources of content and inspiration
"The Gift of Observation: An Interview with Mary Lyon" by Jane Gitschier published in 2010 in the journal PLoS Genetics at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809768/
"Mary Lyon: The Geneticist Who Discovered That Women Are (Cellular) Mosaics" by Manuel Ruiz Rejon published in 2020 in OpenMind at https://www.bbvaopenmind.com/en/science/leading-figures/mary-lyon-geneticist-discovered-women-are-cellular-mosaics/
"Sex Chromosomes in Mammals: X Inactivation" by John Wing and Claire O'Connor published in 2008 in the journal Nature Education at https://www.nature.com/scitable/topicpage/sex-chromosomes-in-mammals-x-inactivation-522/
Credits
Cover art and newsletter design by Abby Armato
Intro and outro music "In My Dreams" by Freebeats.io
Contact the pod at brainbreakroompod@gmail.com
Sign up for the newsletter at http://eepurl.com/hS0FbL
This episode answers the question of how our bodies avoid absolute chaos when we have two X chromosomes. Featuring the story of a brilliant female scientist - Dr. Mary Lyon, the experiments that led to her breakthrough discovery, and how it is helping patients today. Cat-lovers, never fear, the magic and mystery of calico cats is also covered!
Sources of content and inspiration
"The Gift of Observation: An Interview with Mary Lyon" by Jane Gitschier published in 2010 in the journal PLoS Genetics at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809768/
"Mary Lyon: The Geneticist Who Discovered That Women Are (Cellular) Mosaics" by Manuel Ruiz Rejon published in 2020 in OpenMind at https://www.bbvaopenmind.com/en/science/leading-figures/mary-lyon-geneticist-discovered-women-are-cellular-mosaics/
"Sex Chromosomes in Mammals: X Inactivation" by John Wing and Claire O'Connor published in 2008 in the journal Nature Education at https://www.nature.com/scitable/topicpage/sex-chromosomes-in-mammals-x-inactivation-522/
Credits
Cover art and newsletter design by Abby Armato
Intro and outro music "In My Dreams" by Freebeats.io
Contact the pod at brainbreakroompod@gmail.com
Sign up for the newsletter at http://eepurl.com/hS0FbL